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MXenes for Cancer Therapy and Diagnosis: Recent Advances and Current Challenges

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15640%2F21%3A73607179" target="_blank" >RIV/61989592:15640/21:73607179 - isvavai.cz</a>

  • Result on the web

    <a href="https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c01763" target="_blank" >https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c01763</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acsbiomaterials.0c01763" target="_blank" >10.1021/acsbiomaterials.0c01763</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    MXenes for Cancer Therapy and Diagnosis: Recent Advances and Current Challenges

  • Original language description

    MXenes endowed with several attractive physicochemical attributes, namely, specific large surface area, significant electrical conductivity, magnetism, low toxicity, luminescence, and high biocompatibility, have been considered as promising candidates for cancer therapy and theranostics. These two-dimensional (2D) nanostructures endowed with photothermal, chemotherapeutic synergistic, and photodynamic effects have shown promising potential for decidedly effectual and noninvasive anticancer treatments. They have been explored for photothermal/chemo-photothermal therapy (PTT) and for targeted anticancer drug delivery. Remarkably, MXenes with their unique optical properties have been employed for bioimaging and biosensing, and their excellent light-to-heat transition competence renders them an ideal biocompatible and decidedly proficient nanoscaled agent for PTT appliances. However, several important challenging issues still linger regarding their stability in physiological environments, sustained/controlled release of drugs, and biodegradability that need to be addressed. This Perspective emphasizes the latest advancements of MXenes and MXene-based materials in the domain of targeted cancer therapy/diagnosis, with a focus on the current trends, important challenges, and future perspectives.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    21001 - Nano-materials (production and properties)

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ACS Biomaterials Science &amp; Engineering

  • ISSN

    2373-9878

  • e-ISSN

  • Volume of the periodical

    2021

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    14

  • Pages from-to

    1900-1913

  • UT code for WoS article

    000662265300001

  • EID of the result in the Scopus database

    2-s2.0-85105101661