Reference intervals in evaluation of maternal thyroid function during the first trimester of pregnancy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A4660" target="_blank" >RIV/00216208:11110/09:4660 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/09:4660

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Reference intervals in evaluation of maternal thyroid function during the first trimester of pregnancy

Original language description

Insufficient function of the thyroid gland can cause low concentrations of thyroid gland hormones which are necessary for the proper development of the foetus brain, especially during the beginning of pregnancy. We determined the reference interval for TSH in the first trimester of pregnancy and the decision point for anti-TPO antibodies? positivity. We tested 5520 women from the central part of the Czech Republic during the first trimester of pregnancy for serum TSH, anti-TPO and FT4 by chemiluminometric immunoanalysis on an ADVIA Centaur system (Siemens). The reference interval for TSH was determined to be 0.06?3.67 mU/l. The suppression of TSH was found in 2.93% of the women; a raised concentration of TSH had been found in 4.48% of the women. For anti-TPO, the cut-off was established at 143 kU/l; 11.2% of the pregnant women were found to be anti-TPO positive.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

—

Project

—

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Endocrinology

ISSN

0804-4643

e-ISSN

—

Volume of the periodical

160

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

—

UT code for WoS article

000272934500010

EID of the result in the Scopus database

—