Occupational Trichloroethylene Exposure and Renal Carcinoma Risk: Evidence of Genetic Susceptibility by Reductive Metabolism Gene Variants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A7404" target="_blank" >RIV/00216208:11110/10:7404 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/10:10213244 RIV/00209805:_____/10:#0000263

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Occupational Trichloroethylene Exposure and Renal Carcinoma Risk: Evidence of Genetic Susceptibility by Reductive Metabolism Gene Variants

Original language description

We conducted a case-control study in Central Europe (1,097 cases and 1,476 controls) specifically designed to assess risk associated with occupational exposure to TCE through analysis of detailed job histories. Our results provide the strongest evidenceto date that TCE exposure is associated with increased renal cancer risk, particularly among individuals carrying polymorphisms in genes that are important in the reductive metabolism of this chemical.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FM - Hygiene

OECD FORD branch

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Project

<a href="/en/project/NS10290" target="_blank" >NS10290: Epidemiologic study of genetic and behavioral risk factors in kidney cancer</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cancer Research

ISSN

0008-5472

e-ISSN

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Volume of the periodical

70

Issue of the periodical within the volume

16

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

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UT code for WoS article

000280887000015

EID of the result in the Scopus database

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