Occupational exposure to organic dust and risk of lymphoma subtypes in the EPILYMPH case-control study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F21%3A00078501" target="_blank" >RIV/00209805:_____/21:00078501 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/21:00124641
Result on the web
<a href="https://pubmed.ncbi.nlm.nih.gov/33103203/" target="_blank" >https://pubmed.ncbi.nlm.nih.gov/33103203/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5271/sjweh.3925" target="_blank" >10.5271/sjweh.3925</a>
Alternative languages
Result language
angličtina
Original language name
Occupational exposure to organic dust and risk of lymphoma subtypes in the EPILYMPH case-control study
Original language description
bjectives This study aimed to estimate the risk of lymphoma and its major subtypes in relation to occupational exposure to specific organic dusts. Methods We explored the association in 1853 cases and 1997 controls who participated in the EpiLymph case-control study, conducted in six European countries in 1998-2004. Based on expert assessment of lifetime occupational exposures, we calculated the risk of the major lymphoma subtypes associated with exposure to six specific organic dusts, namely, flour, hardwood, softwood, natural textile, synthetic textile, and leather, and two generic (any types) groups: wood and textile dusts. Risk was predicted with unconditional regression modeling, adjusted by age, gender, study center, and education. Results We observed a 2.1-fold increase in risk of follicular lymphoma associated with ever exposure to leather dust [95% confidence interval (CI) 1.01-4.20]. After excluding subjects who ever worked in a farm or had ever been exposed to solvents, risk of B-cell lymphoma was elevated in relation to ever exposure to leather dust [odd ratio (OR) 2.2, 95% CI 1.00-4.78], but it was not supported by increasing trends with the exposure metrics. Risk of Hodgkin lymphoma was elevated (OR 2.0, 95% CI 0.95-4.30) for exposure to textile dust, with consistent upward trends by cumulative exposure and three independent exposure metrics combined (P=0.023, and P=0.0068, respectively). Conclusions Future, larger studies might provide further insights into the nature of the association we observed between exposure to textile dust and risk of Hodgkin lymphoma.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scandinavian journal of work, environment & health
ISSN
0355-3140
e-ISSN
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Volume of the periodical
47
Issue of the periodical within the volume
1
Country of publishing house
FI - FINLAND
Number of pages
10
Pages from-to
42-51
UT code for WoS article
000600200200006
EID of the result in the Scopus database
2-s2.0-85099073429