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Intrinsic nitric oxide-stimulatory activity of lipoteichoic acids from different Gram-positive bacteria

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A8674" target="_blank" >RIV/00216208:11110/10:8674 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/10:00348719

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Intrinsic nitric oxide-stimulatory activity of lipoteichoic acids from different Gram-positive bacteria

  • Original language description

    The cell wall of Gram-positive bacteria conain large amounts of lipoteichoic acid (LTA). We have found that LTA is endowed with immunostimulatory properties, the expression of which depends on its bacterial source. It has been demonstrated LTA shows positive response in Limulus amoebocyte assay (LAL), mimicking thus lipopolysaccharide (LPS) of Gram-negative bacteria. Similar to LPS, LTA binds to the antibiotics polymyxinB.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA305%2F08%2F0535" target="_blank" >GA305/08/0535: Interference of probiotics with factors determining pharmacokinetics of drugs</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nitric Oxide - Biology and Chemistry

  • ISSN

    1089-8603

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

  • UT code for WoS article

    000283894500008

  • EID of the result in the Scopus database