Leptin and adiponectin in pancreatic cancer: connection with diabetes mellitus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A10020" target="_blank" >RIV/00216208:11110/11:10020 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/11:10020
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/21067267" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21067267</a>
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Leptin and adiponectin in pancreatic cancer: connection with diabetes mellitus
Original language description
The aim of this study was to analyze the relationship of serum leptin as well as adiponectin and the manifestation of pancreatic cancer (PC). Serum leptin, adiponectin, glucose homeostasis and insulin resistance (expressed as HOMA-IR) were investigated in 64 patients with newly diagnosed PC and compared with 64 healthy controls (CON group) and 75 patients with type 2 diabetes (DM2). Seventy percent of newly diagnosed PC patients had DM2. The levels of leptin were lower, whilst adiponectin/leptin ratio was higher in PC patients (both with and without DM2), in comparison with CON and DM2 groups (P < 0.001) independently of age, BMI and waist circumference. Newly diagnosed PC is characterized with lower leptin concentrations and higher adiponectin/leptinratio in comparison with CON or DM2 individuals. Analysis of these parameters could help in the screening of persons in high risk for PC, especially in those with DM2.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/NR9528" target="_blank" >NR9528: Glucose homeostasis disorders and pancreatic cancer: new genetic and nutrition markers related to its occurrence and prognosis</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neoplasma
ISSN
0028-2685
e-ISSN
—
Volume of the periodical
58
Issue of the periodical within the volume
1
Country of publishing house
SK - SLOVAKIA
Number of pages
7
Pages from-to
58-64
UT code for WoS article
000290695500009
EID of the result in the Scopus database
—