No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A10543" target="_blank" >RIV/00216208:11110/11:10543 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/11:00003335 RIV/00216208:11130/11:7031 RIV/00064165:_____/11:10543 RIV/00064173:_____/11:#0000169
Result on the web
<a href="http://dx.doi.org/10.1016/j.leukres.2011.04.001" target="_blank" >http://dx.doi.org/10.1016/j.leukres.2011.04.001</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma
Original language description
The role of the TP53 gene's R72P polymorphism in non-Hodgkin lymphoma (NHL) has been analyzed in several studies but it has not been studied in Hodgkin lymphoma (HL). We have evaluated the role of R72P in 340 NHL and 298 HL patients. There was no difference in the R72P frequency between analyzed lymphoma cases and 749 controls. We found no association of R72P with the risk of NHL and HL development [OR(ArgPro/ProPro)=0.9 (95% CI 0.7-1.2) and 1.2 (95% CI 0.9-1.5), respectively] or with survival. Our results support the evidence that R72P is not a prognostic factor in Caucasian NHL patients, and they indicate its irrelevance for HL development or prognosis.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Leukemia Research
ISSN
0145-2126
e-ISSN
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Volume of the periodical
35
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
3
Pages from-to
1117-1119
UT code for WoS article
000292735300026
EID of the result in the Scopus database
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