The Peptidic GHS-R antagonist [D-Lys(3)]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9407" target="_blank" >RIV/00216208:11110/11:9407 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/11:00363114 RIV/00064165:_____/11:9407
Result on the web
<a href="http://dx.doi.org/10.1016/j.mce.2011.06.006" target="_blank" >http://dx.doi.org/10.1016/j.mce.2011.06.006</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The Peptidic GHS-R antagonist [D-Lys(3)]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity
Original language description
It was demonstrated that estrogen deficiency and consuming high fat (HF) diet enhanced orexigenic activity of ghrelin. Therefore, we hypothesized that antagonizing of ghrelin action would attenuate food intake and body weight in mice obese both from ovariectomy (OVX) and feeding a HF diet.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
<a href="/en/project/GA303%2F09%2F0744" target="_blank" >GA303/09/0744: Impact of ghrelin and estrogen on metabolic syndrom of female obese mice</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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