Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9496" target="_blank" >RIV/00216208:11110/11:9496 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/11:9496
Result on the web
<a href="http://dx.doi.org/10.1111/j.1600-0897.2010.00959.x" target="_blank" >http://dx.doi.org/10.1111/j.1600-0897.2010.00959.x</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Intracellular Cytokine Production in Peripheral Blood Lymphocytes: A Comparison of Values in Infertile and Fertile Women
Original language description
To analyze the relation of the fertility and pregnancy of women of childbearing age to the intracellular (IC) production of tumor necrosis factor alpha (TNF-alpha), interferon gamma (IFN-gamma), and interleukins 2 and 4 (IL-2 and IL-4). Intracellular cytokine production in peripheral blood CD3(+) CD4(+)lymphocytes was analyzed by flow cytometry in 185 women being treated for infertility and 50 fertile women of childbearing age. Infertile women have a significantly higher IC production of TNF-alpha, IFN-gamma, IL-2, and IL-4 and higher ratios of TNF-alpha/IL-2, TNF-alpha/IL-4, and TNF-alpha/IFN-gamma compared to the fertile women. Cytokines produced by Th lymphocytes are important in orchestrating the immune response during conception, and Th-cell dysregulation could be a reason for infertility.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American Journal of Reproductive Immunology
ISSN
1046-7408
e-ISSN
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Volume of the periodical
65
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
466-469
UT code for WoS article
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EID of the result in the Scopus database
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