Serum cytokine profile in patients with active lupus nephritis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11463" target="_blank" >RIV/00216208:11110/12:11463 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/12:11463
Result on the web
<a href="http://dx.doi.org/10.1016/j.cyto.2012.07.004" target="_blank" >http://dx.doi.org/10.1016/j.cyto.2012.07.004</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Serum cytokine profile in patients with active lupus nephritis
Original language description
Purpose: Determination of disease activity of lupus nephritis remains challenging. Since cytokines play a role as inflammatory mediators extending renal injury, measuring serum cytokine levels might help in the clinical assessment of patients with lupusnephritis. Therefore, the aim of this study was to determine the diagnostic value of a panel of serum cytokines in patients with active lupus nephritis. Methods: In this prospective controlled multicenter trial, sera of 12 patients with active lupus nephritis were collected in a clinical routine setting at the time of renal biopsy and 6 months afterwards. Fourteen patients with inactive systemic lupus erythematosus (SLE), and 14 healthy subjects were used as controls. Eleven cytokines IL-5, IL-6, IL-10,IL-12(p40), IL-12(p70), IL-18, INF-alpha, TGF-beta 1, IFN-alpha 2, IFN-gamma) and two soluble receptors (IL-1ra and TNF-RII) were measured by cytokine multiplex assay. Results: In inactive SLE patients, serum levels of IL-10, IL-12(p40),
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cytokine
ISSN
1043-4666
e-ISSN
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Volume of the periodical
60
Issue of the periodical within the volume
2
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
410-416
UT code for WoS article
000310494300014
EID of the result in the Scopus database
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