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Nutritional hepatic iron overload is not prevented by parenteral hepcidin substitution therapy in mice.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11517" target="_blank" >RIV/00216208:11110/12:11517 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1017/S0007114512000116" target="_blank" >http://dx.doi.org/10.1017/S0007114512000116</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nutritional hepatic iron overload is not prevented by parenteral hepcidin substitution therapy in mice.

  • Original language description

    We tested whether multiple doses of intraperitoneally administered hepcidin can prevent hepatic iron levels. Renatured synthetic hepcidin significantly decreased transferrin saturation but did not prevent hepatic Fe overload in mice fed the Fe-rich diet,nor did it affect hepatic Fe stores in mice fed the normal diet.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS10300" target="_blank" >NS10300: Therapeutic and diagnostic potential of hepcidin.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    British Journal of Nutrition

  • ISSN

    0007-1145

  • e-ISSN

  • Volume of the periodical

    108

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    3

  • Pages from-to

    1723-1725

  • UT code for WoS article

    000311399400001

  • EID of the result in the Scopus database