Bone Mineral Density and Body Composition in Men With Multiple Sclerosis Chronically Treated With Low-Dose Glucocorticoids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A11549" target="_blank" >RIV/00216208:11110/12:11549 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/12:10124942 RIV/00064165:_____/12:11549

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/61/61_405.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/61/61_405.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Bone Mineral Density and Body Composition in Men With Multiple Sclerosis Chronically Treated With Low-Dose Glucocorticoids

Original language description

The aim of the study was to compare the bone mineral density (BMD) and body composition between ambulatory male MS patients and control subjects and to evaluate the relationships among body composition, motor disability, glucocorticoids (GC) use, and bone health. Body composition and BMD were measured by dual-energy X-ray absorptiometry in 104 ambulatory men with MS (mean age: 45.2 years) chronically treated with low-dose GC and in 54 healthy age-matched men. Compared to age-matched controls, MS patients had a significantly lower total body bone mineral content (TBBMC) and BMD at all measured sites except for the radius. Sixty five male MS patients (62.5%) met the criteria for osteopenia and twenty six of them (25%) for osteoporosis. The multivariate analysis showed a consistent dependence of bone measures (except whole body BMD) on BMI. The total leg lean mass % was as an independent predictor of TBBMC. The Expanded Disability Status Scale (EDSS), cumulative GC dose and age were indep

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/NS10564" target="_blank" >NS10564: Bone mineral density, bone turnover and body composition in multiple sclerosis patients long-term treated with glucocorticoids: relationships with vitamin D receptor allelic polymorphisms</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

61

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

13

Pages from-to

405-417

UT code for WoS article

000309194600009

EID of the result in the Scopus database

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