Eighteen-Year Effect of Androgen Therapy on Bone Mineral Density in Trans(gender) Men
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10376402" target="_blank" >RIV/00216208:11110/18:10376402 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1055/s-0043-118747" target="_blank" >https://doi.org/10.1055/s-0043-118747</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/s-0043-118747" target="_blank" >10.1055/s-0043-118747</a>
Alternative languages
Result language
angličtina
Original language name
Eighteen-Year Effect of Androgen Therapy on Bone Mineral Density in Trans(gender) Men
Original language description
The study explores the influence of long-term androgen supplementation (18 years) on bone metabolism in trans(gender) men. Thirty five trans(gender) men aged (47 +/- 4) were treated with adequate dose of testosterone. BMD was measured by DEXA at lumbar spine and neck and T score was determined. Biochemical parameters of bone turnover were measured in all patients. As compared with female and male age matched controls they showed a not significantly different T-score at spine [1.213 +/- 0.15 in trans(gender) men vs. 1.192 +/- 0.19 in females and 1.203 +/- 0.06g/cm (2) in males (p<0.01)]. BMD in the hip skeleton in trans(gender) men (0.950 +/- g/cm (2) ) was statistically higher than females (0.822 +/- 0.09) but not statistically different from normal males 0.988 +/- 0.06). Circulating biochemical markers of bone formation, and resorption were not different between the trans(gender) men, and matched controls. We conclude that BMD at the hip (site rich in cortical bone) after adequate dose of testosterone therapy is higher while it is not different at the spine (trabecular bone) in trans(gender) men even after 18 years of testosterone administration.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Hormone and Metabolic Research
ISSN
0018-5043
e-ISSN
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Volume of the periodical
50
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
5
Pages from-to
133-137
UT code for WoS article
000424159700005
EID of the result in the Scopus database
2-s2.0-85041524587