Anti-infective and herbicidal activity of N-substituted 2-aminobenzothiazoles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12347" target="_blank" >RIV/00216208:11110/12:12347 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/12:10133746 RIV/62157124:16370/12:43871028 RIV/00179906:_____/12:10133746
Result on the web
<a href="http://dx.doi.org/10.1016/j.bmc.2012.10.007" target="_blank" >http://dx.doi.org/10.1016/j.bmc.2012.10.007</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Anti-infective and herbicidal activity of N-substituted 2-aminobenzothiazoles
Original language description
In this study, a series of N-substituted 2-aminobenzothiazoles was prepared according to a recently developed method. Twelve compounds were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary in vitro screening of the discussed compounds was also performed against fungal, bacterial and mycobacterial species. The biological activities of some compounds were comparable or higher than the standards phenoxymethylpenicillin or pyrazinamide. The most effective compounds demonstrated insignificant toxicity against the human monocytic leukemia THP-1 cell line. For all compounds, the structure-activity relationships are discussed.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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