Adiponectin relation to skin changes and dyslipidemia in systemic sclerosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12353" target="_blank" >RIV/00216208:11110/12:12353 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/12:12353 RIV/00023728:_____/12:#0004122
Result on the web
<a href="http://dx.doi.org/10.1016/j.cyto.2012.02.003" target="_blank" >http://dx.doi.org/10.1016/j.cyto.2012.02.003</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Adiponectin relation to skin changes and dyslipidemia in systemic sclerosis
Original language description
Adiponectin was initially described as a regulator of metabolic homeostases. Further studies demonstrated its involvement in the regulation of inflammatory diseases, particularly rheumatic and vascular diseases and some fibrotic processes. The aim of this study was to evaluate adiponectin in the circulation of patients with systemic sclerosis (SSc) and characterise its potential association with skin changes and SSc-related features.Adiponectin serum levels were similar between patients with SSc and healthy controls. Levels of serum adiponectin were negatively correlated with the skin score. Regression analysis of the relationship between adiponectin and markers of interest provided two statistically significant models: A- with explanatory variables HDL-cholesterol, skin score, disease duration, age (R(2)=0.580); and B- with CRP, skin score, age in order of a decreasing influence. Based on the results of this study, it might be speculated that adiponectin plays a protective role in ski
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cytokine
ISSN
1043-4666
e-ISSN
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Volume of the periodical
58
Issue of the periodical within the volume
2
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
165-168
UT code for WoS article
000303099200006
EID of the result in the Scopus database
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