Sentinel lymph node status in patients with locally advanced cervical cancers and impact of neoadjuvant chemotherapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12396" target="_blank" >RIV/00216208:11110/12:12396 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/12:00060412 RIV/00064165:_____/12:12396

Result on the web

<a href="http://dx.doi.org/10.1016/j.ygyno.2012.02.010" target="_blank" >http://dx.doi.org/10.1016/j.ygyno.2012.02.010</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Sentinel lymph node status in patients with locally advanced cervical cancers and impact of neoadjuvant chemotherapy

Original language description

Objectives. Neoadjuvant chemotherapy (NAC) is used in locally advanced cervical cancers with the aim to decrease the size of the tumor and to allow for less radical surgery. Despite of the fact that the high response rate of the tumor has been well established, the impact of NAC on sentinel lymph node (SN) detection and status has not been explored to date. Methods. Our study included 82 patients with locally advanced cervical cancers (FIGO IB1 >3 cm, IB2, IIA2 and selected IIB) out of which 51 patientswere referred to SN biopsy prior to NAC and 31 patients to radical surgical procedure including SN biopsy after three courses of "dose density" NAC. In both groups, the prevalence of macrometastases, micrometastases and isolated tumor cells (ITC) in SNwas compared. Results. The total of 179 SNs was evaluated. SN detection rate in the whole cohort reached 87.8% per patient and 60.9% bilaterally, without significant difference between both groups. In the group with upfront SN biopsy prio

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Gynecologic Oncology

ISSN

0090-8258

e-ISSN

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Volume of the periodical

125

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

303-306

UT code for WoS article

000303227500005

EID of the result in the Scopus database

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