Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12689" target="_blank" >RIV/00216208:11110/12:12689 - isvavai.cz</a>
Result on the web
<a href="http://ard.bmj.com/content/71/5/785" target="_blank" >http://ard.bmj.com/content/71/5/785</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis
Original language description
Inhibition of hedgehog signalling exerted potent antifibrotic effects in preclinical models of SSc in both preventive and therapeutic settings. These findings might have direct translational implications because inhibitors of Smo are already available and yielded promising results in initial clinical trials.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Annals of Rheumatic Diseases
ISSN
0003-4967
e-ISSN
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Volume of the periodical
71
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
785-789
UT code for WoS article
000302634000026
EID of the result in the Scopus database
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