Distinctive histopathological features that support a diagnosis of cholesterol ester storage disease in liver biopsy specimens

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12691" target="_blank" >RIV/00216208:11110/12:12691 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/12:12691

Result on the web

<a href="http://dx.doi.org/10.1111/j.1365-2559.2011.04164.x" target="_blank" >http://dx.doi.org/10.1111/j.1365-2559.2011.04164.x</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Distinctive histopathological features that support a diagnosis of cholesterol ester storage disease in liver biopsy specimens

Original language description

We analyzed a series of 16 liver biopsies of lysosomal acid lipase (LAL) deficiency of the cholesterol ester storage disease (CESD) type confirmed by enzyme testing and DNA sequencing to identify reliable criteria to improve the differential diagnosis between lysosomal accumulation of neutral lipids and non-lysosomal steatosis. The pathological diagnosis of CESD can be rapidly and effectively appreciated at the light microscopy level, even in routine fixed paraffin-embedded liver samples with immmunohistochemical staining for lysosomal markers.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EA - Morphology and cytology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Histopathology

ISSN

0309-0167

e-ISSN

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Volume of the periodical

60

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

1107-1113

UT code for WoS article

000304344300009

EID of the result in the Scopus database

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