Combined Inhibition of c-Abl and PDGF Receptors for Prevention and Treatment of Murine Sclerodermatous Chronic Graft-versus-Host Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12719" target="_blank" >RIV/00216208:11110/12:12719 - isvavai.cz</a>
Alternative codes found
RIV/00023728:_____/12:#0004128
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0002944012005822" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0002944012005822</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Combined Inhibition of c-Abl and PDGF Receptors for Prevention and Treatment of Murine Sclerodermatous Chronic Graft-versus-Host Disease
Original language description
We examined the effects of the combined inhibition of the Abelson kinase (c-Abl) and platelet-derived growth factor receptors (PDGFR) in experimental sclerodermatous cGvHD. Treatment using imatinib or nilotinib abolished the aberrant activation of c-Abland PDGFR and protected against experimental cGvHD.Prozkoumali jsme účinky kombinované inhibice c-Abl a PDGFR u experimentální sklerodermatozní cGvHD. Léčba pomocí imatinibu nebo nilotinibu zabránila zvýšené aktivaci c-Abl a PDGFR a rozvoji experimentální cGvHD
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American Journal of Pathology
ISSN
0002-9440
e-ISSN
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Volume of the periodical
181
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
1672-1680
UT code for WoS article
000310656800018
EID of the result in the Scopus database
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