Long-term survival of patients suffering from glioblastoma multiforme treated with tumor-treating fields

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A13558" target="_blank" >RIV/00216208:11110/12:13558 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/12:43906566

Result on the web

<a href="http://dx.doi.org/10.1186/1477-7819-10-220" target="_blank" >http://dx.doi.org/10.1186/1477-7819-10-220</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Long-term survival of patients suffering from glioblastoma multiforme treated with tumor-treating fields

Original language description

Glioblastoma multiforme (GBM) is the most common and malignant primary intracranial tumor, and has a median survival of only 10 to 14 months with only 3 to 5% of patients surviving more than three years. Recurrence (RGBM) is nearly universal, and furtherdecreases the median survival to only five to seven months with optimal therapy. Tumor-treating fields (TTField) therapy is a novel treatment technique that has recently received CE and FDA approval for the treatment of RGBM, and is based on the principle that low intensity, intermediate frequency electric fields (100 to 300 kHz) may induce apoptosis in specific cell types. Our center was the first to apply TTField treatment to histologically proven GBM in a small pilot study of 20 individuals in 2004and 2005, and four of those original 20 patients are still alive today. We report two cases of GBM and two cases of RGBM treated by TTField therapy, all in good health and no longer receiving any treatment more than seven years after init

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

World Journal of Surgical Oncology

ISSN

1477-7819

e-ISSN

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Volume of the periodical

10

Issue of the periodical within the volume

Article Number: 220

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

1-6

UT code for WoS article

000311962700001

EID of the result in the Scopus database

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