Response Patterns of Recurrent Glioblastomas Treated With Tumor-Treating Fields

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10293195" target="_blank" >RIV/00216208:11110/14:10293195 - isvavai.cz</a>

Alternative codes found

RIV/00023884:_____/14:#0007180

Result on the web

<a href="http://dx.doi.org/10.1053/j.seminoncol.2014.09.009" target="_blank" >http://dx.doi.org/10.1053/j.seminoncol.2014.09.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.seminoncol.2014.09.009" target="_blank" >10.1053/j.seminoncol.2014.09.009</a>

Result language

angličtina

Original language name

Response Patterns of Recurrent Glioblastomas Treated With Tumor-Treating Fields

Original language description

Glioblastoma multiforme (GBM) is the most common form of primary malignant brain cancer. Median overall survival (OS) for newly diagnosed patients is only about 12 to 18 months. GBM tumors invariably recur, and there is no widely recognized and effectivestandard treatment for recurrent GBM. NovoTTF Therapy is a novel and US Food and Drug Administration (FDA)-approved antimitotic treatment for recurrent GBM with potential benefits compared with other options. Recurrent GBM patients from two prior trialswith demonstrated radiologic tumor response to single-agent NovoTTF Therapy were analyzed to better characterize tumor response patterns and evaluate the associations between response, compliance, and OS. In addition, a compartmental tumor growth modelwas developed and evaluated for its ability to predict GBM response to tumor-treating fields (TTFields). The overall response rate across both trials was 15% (4% complete responses): 14% in the phase III trial (14/120) and 20% (2/10) in a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Seminars in Oncology

ISSN

0093-7754

e-ISSN

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Volume of the periodical

41

Issue of the periodical within the volume

October

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

"S14"-"S24"

UT code for WoS article

000344310000003

EID of the result in the Scopus database

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