Adipocytes derived fibrinolytic components in peritoneum - a pilot study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A13581" target="_blank" >RIV/00216208:11110/12:13581 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/12:10123284
Result on the web
<a href="http://dx.doi.org/10.2478/s11536-012-0042-8" target="_blank" >http://dx.doi.org/10.2478/s11536-012-0042-8</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Adipocytes derived fibrinolytic components in peritoneum - a pilot study
Original language description
The proteins of the fibrinolytic system - urokinase plasminogen activator(uPA), tissue plasminogen activator (tPA)and plasminogen activator inhibitor type IPAI-I) - play important roles in fibrotization in various organs and including peritoneum. To study the cellular localization of PAI-1, tPA and uPA within the adipose tissue of the peritoneal membrane in patients at the onset of peritoneal dialysis(PD) we determined the initial expression of these proteins in relationship to multiple clinical variables. Methods: routinely performed parietal peritoneal biopsies in 12 patients undergoing peritoneal catheter implantation were examined. We used formalinfixed, paraffin-embedded specimens for immunohistochemical localization of these proteins along with the stereological pointcounting method for quantification of their expression within the peritoneal adipose tissue. Results: strong positive mutual correlation between the expression of PAI-1 and both uPA (SpearmanR=0.66) and tPA (R=0.59)
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Central European Journal of Medicine
ISSN
1895-1058
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
5
Country of publishing house
PL - POLAND
Number of pages
6
Pages from-to
604-609
UT code for WoS article
000307255900008
EID of the result in the Scopus database
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