Dopamine 2 receptor expression in various pathological types of clinically non-functioning pituitary adenomas
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A8785" target="_blank" >RIV/00216208:11110/12:8785 - isvavai.cz</a>
Alternative codes found
RIV/61383082:_____/12:#0000103 RIV/00216208:11150/12:10125041 RIV/00179906:_____/12:10125041 RIV/00064165:_____/12:8785
Result on the web
<a href="http://dx.doi.org/10.1007/s11102-011-0316-1" target="_blank" >http://dx.doi.org/10.1007/s11102-011-0316-1</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Dopamine 2 receptor expression in various pathological types of clinically non-functioning pituitary adenomas
Original language description
Clinically non-functioning pituitary adenomas account for about one-third of pituitary tumors. The majority of them are pathologically classified as gonadotropinomas or null-cell adenomas without hormonal expression. The rest represent silent corticotroph adenomas and plurihormonal tumors. Conservative therapy with dopamine agonists is effective in some cases only depending on the expression of dopamine 2 receptors (D2R). The aim of this study was to quantitatively estimate D2R expression in clinicallynon-functioning pituitary adenomas and correlate the results with adenoma type according to pathological classification. Out of the 87 adenomas investigated, 63 expressed gonadotropins, 7 were silent corticotroph adenomas, 7 were plurihormonal tumors, and only 6 did not express any pituitary hormone on immunohistochemical investigation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11344" target="_blank" >NT11344: Quantitative analysis of somatostatin receptors in pituitary adenomas.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pituitary
ISSN
1386-341X
e-ISSN
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Volume of the periodical
15
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
222-226
UT code for WoS article
000304405400016
EID of the result in the Scopus database
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