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Dopamine 2 receptor expression in various pathological types of clinically non-functioning pituitary adenomas

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A8785" target="_blank" >RIV/00216208:11110/12:8785 - isvavai.cz</a>

  • Alternative codes found

    RIV/61383082:_____/12:#0000103 RIV/00216208:11150/12:10125041 RIV/00179906:_____/12:10125041 RIV/00064165:_____/12:8785

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s11102-011-0316-1" target="_blank" >http://dx.doi.org/10.1007/s11102-011-0316-1</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Dopamine 2 receptor expression in various pathological types of clinically non-functioning pituitary adenomas

  • Original language description

    Clinically non-functioning pituitary adenomas account for about one-third of pituitary tumors. The majority of them are pathologically classified as gonadotropinomas or null-cell adenomas without hormonal expression. The rest represent silent corticotroph adenomas and plurihormonal tumors. Conservative therapy with dopamine agonists is effective in some cases only depending on the expression of dopamine 2 receptors (D2R). The aim of this study was to quantitatively estimate D2R expression in clinicallynon-functioning pituitary adenomas and correlate the results with adenoma type according to pathological classification. Out of the 87 adenomas investigated, 63 expressed gonadotropins, 7 were silent corticotroph adenomas, 7 were plurihormonal tumors, and only 6 did not express any pituitary hormone on immunohistochemical investigation.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT11344" target="_blank" >NT11344: Quantitative analysis of somatostatin receptors in pituitary adenomas.</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Pituitary

  • ISSN

    1386-341X

  • e-ISSN

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    222-226

  • UT code for WoS article

    000304405400016

  • EID of the result in the Scopus database