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Sex, Food and Threat: Startling Changes after Subthalamic Stimulation in Parkinson's Disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10189558" target="_blank" >RIV/00216208:11110/13:10189558 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21230/13:00208419 RIV/00064165:_____/13:10189558 RIV/00023884:_____/12:00007608

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.brs.2013.03.009" target="_blank" >http://dx.doi.org/10.1016/j.brs.2013.03.009</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.brs.2013.03.009" target="_blank" >10.1016/j.brs.2013.03.009</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sex, Food and Threat: Startling Changes after Subthalamic Stimulation in Parkinson's Disease

  • Original language description

    Background: Changes in motivational processing may play a role in weight gain and other non-motor side effects in Parkinson's disease (PD) patients treated with deep brain stimulation of the subthalamic nucleus. Objective/hypothesis: We aimed to assess changes in aversive and appetitive motivational activation using modulation of the acoustic blink reflex (ABR) by rewarding and aversive stimuli. Methods: ABR elicited during the viewing of erotic, food, aversive and neutral pictures was recorded in 11 off-medicated patients with the subthalamic stimulation switched ON and OFF, and in 11 control subjects. Results: ABR to erotic stimuli was larger in patients in the ON compared to the OFF condition and controls (P < 0.01). Aversive stimuli caused a largerincrease in the ABR in patients with the ON condition than in controls (P < 0.05). Additionally, we found a negative correlation of the ABR magnitude to food pictures in the ON condition with weight gain following subthalamic stimulation

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Brain Stimulation

  • ISSN

    1935-861X

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    6

  • Pages from-to

    740-745

  • UT code for WoS article

    000325046600006

  • EID of the result in the Scopus database