Prediction of recurrence in low and intermediate risk non-muscle invasive bladder cancer by real-time quantitative PCR analysis: cDNA microarray results

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10190314" target="_blank" >RIV/00216208:11110/13:10190314 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/13:10190314 RIV/00064203:_____/13:10190314 RIV/00064165:_____/13:10190314
Result on the web
<a href="http://dx.doi.org/10.4149/neo_2013_0391" target="_blank" >http://dx.doi.org/10.4149/neo_2013_0391</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/neo_2013_0391" target="_blank" >10.4149/neo_2013_0391</a>

Result language
angličtina
Original language name
Prediction of recurrence in low and intermediate risk non-muscle invasive bladder cancer by real-time quantitative PCR analysis: cDNA microarray results
Original language description
The aim of the study was to define specific genetic profile in Ta and Tl urinary bladder carcinoma patients with and without recurrence by gene expression microarrays. Eleven patients with the time to recurrence shorter than one year (patients with recurrence) and 11 patients with time to recurrence longer than 4 years (patients without recurrence) were enrolled. Data from microarrays were subjected to a panel of statistical analyses to identify bladder cancer recurrence-associated gene signatures. Initial screening using the GeneSpring and Bioconductor software tools revealed a putative set 47 genes differing in gene expression in both groups. After the validation, 33 genes manifested significant differences between both groups. The significant expression was observed in the group of patients without recurrence by 30 genes of which the highest differences were detected by ANXA1, ARHGEF4, FLJ32252, GNE, NINJ1, PRICKLE1, PSAT1, RNASE1, SPTAN1, SYNGR1, TNFSF15, TSPAN1, and WDR34. These g
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
—

Project
<a href="/en/project/NT12417" target="_blank" >NT12417: Prospects of MicroRNA, mRNA and FreeDNA for Early Non-invasive Detection and Prognosis Assessment in Urinary Bladder Cancer Patients</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)