Plasma cortisol in Alzheimer's disease with or without depressive symptoms
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10190651" target="_blank" >RIV/00216208:11110/13:10190651 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/13:10190651
Result on the web
<a href="http://dx.doi.org/10.12659/MSM.889110" target="_blank" >http://dx.doi.org/10.12659/MSM.889110</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.12659/MSM.889110" target="_blank" >10.12659/MSM.889110</a>
Alternative languages
Result language
angličtina
Original language name
Plasma cortisol in Alzheimer's disease with or without depressive symptoms
Original language description
Background: Cortisol is presumed to be a risk factor for stress-and age-related disorders, such as depressive disorder and Alzheimer's disease (AD). The aim of this study was to investigate the association of plasma cortisol concentration with AD in presence or absence of comorbid depressive symptoms. Material/Methods: Plasma cortisol concentration was measured in 80 AD patients (35 of them with depressive symptoms), 27 elderly depressive patients without AD, and 37 elderly controls. Results: Compared to controls, a significant increase of mean plasma cortisol was found in AD patients but not in depressive patients. Plasma cortisol was positively correlated with cognitive impairment in AD patients. We confirmed a U-shaped association between plasma cortisol and major depression and a linear association between plasma cortisol and AD without depressive symptoms. Significantly increased relative risk of disease in people with high plasma cortisol was found for AD with depressive symptoms
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medical Science Monitor [online]
ISSN
1643-3750
e-ISSN
—
Volume of the periodical
Neuveden
Issue of the periodical within the volume
19
Country of publishing house
PL - POLAND
Number of pages
9
Pages from-to
681-689
UT code for WoS article
000323181300001
EID of the result in the Scopus database
—