The Role of Resistin in Inflammatory Myopathies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10191411" target="_blank" >RIV/00216208:11110/13:10191411 - isvavai.cz</a>
Alternative codes found
RIV/00023728:_____/13:#0004117
Result on the web
<a href="http://dx.doi.org/10.1007/s11926-013-0336-0" target="_blank" >http://dx.doi.org/10.1007/s11926-013-0336-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11926-013-0336-0" target="_blank" >10.1007/s11926-013-0336-0</a>
Alternative languages
Result language
angličtina
Original language name
The Role of Resistin in Inflammatory Myopathies
Original language description
Both immune and non-immune mechanisms are involved in muscle damage and dysfunction occurring in idiopathic inflammatory myopathies (IIMs). Resistin, originally described as an adipokine linking obesity and insulin resistance in rodents, has been shown apro-inflammatory molecule in humans. Besides its direct effect on production of several inflammatory mediators, resistin influences chemotaxis, migration, proliferation, cell survival, endothelial dysfunction and metabolism - all aspects implicated in the pathogenesis of IIMs. Up-regulation of resistin in muscle tissue and elevated serum resistin levels have been recently demonstrated in patients with IIMs. In addition, serum levels of resistin reflected global disease activity, including extramuscularorgan involvement, in patients with this disease. The aim of this review is therefore to summarize current knowledge about potential implication of resistin in idiopathic inflammatory myopathies.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Rheumatology Reports
ISSN
1523-3774
e-ISSN
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Volume of the periodical
15
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
000324996700007
EID of the result in the Scopus database
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