Resistin in idiopathic inflammatory myopathies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F12%3A12842" target="_blank" >RIV/00216208:11110/12:12842 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/12:8625 RIV/00064203:_____/12:8625 RIV/00023728:_____/12:#0004147

Result on the web

<a href="http://dx.doi.org/10.1186/ar3836" target="_blank" >http://dx.doi.org/10.1186/ar3836</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Resistin in idiopathic inflammatory myopathies

Original language description

Resistin is an adipokine having inflammatory properties in metabolic as well as autoimmune diseases. The purpose of this study was to evaluate and compare the serum levels and local expression of resistin in patients with idiopathic inflammatory myopathies to controls, and to determine the relationship between resistin levels, inflammation and disease activity. The results of this study indicate that higher levels of serum resistin are associated with inflammation, higher global disease activity index and muscle injury in patients with myositis-specific anti-Jo-1 antibody and patients with dermatomyositis. Furthermore, up-regulation of resistin in muscle tissue and resistin-induced synthesis of pro-inflammatory cytokines in mononuclear cells suggest apotential role for resistin in the pathogenesis of inflammatory myopathies.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

<a href="/en/project/NS10614" target="_blank" >NS10614: Predictive value of adipokines in rheuamtoid arthritis</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Arthritis Research & Therapy

ISSN

1478-6354

e-ISSN

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Volume of the periodical

14

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

1-9

UT code for WoS article

000314972600013

EID of the result in the Scopus database

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