Antioxidant Status and Oxidative Stress Markers in Pancreatic Cancer and Chronic Pancreatitis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10192239" target="_blank" >RIV/00216208:11110/13:10192239 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/13:10192239

Result on the web

<a href="http://dx.doi.org/10.1097/MPA.0b013e318288360a" target="_blank" >http://dx.doi.org/10.1097/MPA.0b013e318288360a</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MPA.0b013e318288360a" target="_blank" >10.1097/MPA.0b013e318288360a</a>

Result language

angličtina

Original language name

Antioxidant Status and Oxidative Stress Markers in Pancreatic Cancer and Chronic Pancreatitis

Original language description

Oxidative stress has been implicated in the pathogenesis of chronic pancreatitis (CP) and pancreatic cancer (PC). The study aim was to assess the oxidative stress markers and antioxidant defense system in patients with CP and those with PC. Activities ofsuperoxide dismutase I (SODl), catalase (CAT), glutathione peroxidase I (GPXl), glutathione reductase (GR), arylesterase (PON1-A) and lactonase (PONl-L) activities of paraoxonase 1 (PONl) and concentrations of reduced glutathione, conjugated dienes in low density lipoprotein (CD/LDL) and oxidized LDL (ox-LDL/LDL) were assessed in 50 PC and 50 CP patients and 50 age and sex-matched controls. Comparison of PC and CP groups to controls found the following changes: glulathione peroxidase 1 (GPXl) (-20.2 %,-25.5 %; P < 0.001), glutathione reductase (GR) (-9.5 %, -11.9 %; P < 0.05), SOD1 (+22.9 %; P < 0.01), CAT(-10.6 %; P < 0.05), PON1-A (-34.3 % -16.0 %; P < 0.001), PONl-L (-44.2%; -17.0%; P < 0.01), conjugated dienes in LDL (CD/LDL) (+20

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pancreas

ISSN

0885-3177

e-ISSN

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Volume of the periodical

42

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

614-621

UT code for WoS article

000317655200009

EID of the result in the Scopus database

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