Altered Activities of Antioxidant Enzymes in Patients with Metabolic Syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10192410" target="_blank" >RIV/00216208:11110/13:10192410 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/13:10192410

Result on the web

<a href="http://dx.doi.org/10.1159/000348569" target="_blank" >http://dx.doi.org/10.1159/000348569</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000348569" target="_blank" >10.1159/000348569</a>

Result language

angličtina

Original language name

Altered Activities of Antioxidant Enzymes in Patients with Metabolic Syndrome

Original language description

Objective: In the pathogenesis of the metabolic syndrome (MetS), an increase of oxidative stress could play an important role which is closely linked with insulin resistance, endothelial dysfunction, and chronic inflammation. The aim of our study was toassess several parameters of the antioxidant status in MetS. Methods: 40 subjects with MetS and 40 age- and sex-matched volunteers without MetS were examined for activities of superoxide dismutase (CuZnSOD), catalase (CAT), glutathione peroxidase 1 (GPX1), glutathione reductase (GR), para-oxonase1 (PON1), concentrations of reduced glutathione (GSH), and conjugated dienes in low-density lipoprotein (CD-LDL). Results: Subjects with MetS had higher activities of CuZnSOD (p < 0.05) and GR (p < 0.001), higher concentrations of CD-LDL (p < 0.001), lower activities of CAT (p < 0.05) and PON1 (p < 0.05), and lower concentrations of GSH (p < 0.05), as compared with controls. Activity of GPX1 was not significantly changed. Conclusions: Our result

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/NS9769" target="_blank" >NS9769: Examination of antioxidant status and some polymorphisms of paraoxonase1 in patients with different diseases of pancreas</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Obesity Facts

ISSN

1662-4025

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

1

Country of publishing house

CH - SWITZERLAND

Number of pages

9

Pages from-to

39-47

UT code for WoS article

000315772800005

EID of the result in the Scopus database

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