Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10192849" target="_blank" >RIV/00216208:11110/13:10192849 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/13:00396311 RIV/00216208:11130/13:10192849
Result on the web
<a href="http://dx.doi.org/10.5271/sjweh.3358" target="_blank" >http://dx.doi.org/10.5271/sjweh.3358</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5271/sjweh.3358" target="_blank" >10.5271/sjweh.3358</a>
Alternative languages
Result language
angličtina
Original language name
Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde
Original language description
Objectives Structural chromosomal aberrations in blood lymphocytes represent a biomarker for cellular damage caused by genotoxic carcinogens and are an indicator of increased cancer risk. We evaluated the association between frequencies of total chromosomal aberrations, chromatid- and chromosome-type aberrations, and occupational exposures to volatile anesthetics, antineoplastic agents, and formaldehyde among 601 medical professionals. Methods Chromosomal damage among exposed individuals and unexposed controls was determined by conventional cytogenetic analysis. We used binary logistic regression to evaluate the effects of workplace exposures and major confounders on chromosomal damage. Results Significantly higher frequencies of total chromosomal, chromatid-type and chromosome-type aberrations were observed among subjects occupationally exposed to volatile anesthetics, antineoplastic agents, and formaldehyde compared to age- and sex-matched controls (P<0.0001). The risk of an increase
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scandinavian Journal of Work, Environment and Health
ISSN
0355-3140
e-ISSN
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Volume of the periodical
39
Issue of the periodical within the volume
6
Country of publishing house
FI - FINLAND
Number of pages
13
Pages from-to
618-630
UT code for WoS article
000332916800010
EID of the result in the Scopus database
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