Lipid profiles are associated with lesion formation over 24 months in interferon-beta treated patients following the first demyelinating event

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10193014" target="_blank" >RIV/00216208:11110/13:10193014 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/13:10193014
Result on the web
<a href="http://dx.doi.org/10.1136/jnnp-2012-304740" target="_blank" >http://dx.doi.org/10.1136/jnnp-2012-304740</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1136/jnnp-2012-304740" target="_blank" >10.1136/jnnp-2012-304740</a>

Result language
angličtina
Original language name
Lipid profiles are associated with lesion formation over 24 months in interferon-beta treated patients following the first demyelinating event
Original language description
Objectives: To investigate the associations of serum lipid profile with disease progression in high-risk clinically isolated syndromes (CIS) after the first demyelinating event. Methods: High density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) were obtained in pretreatment serum from 135 high risk patients with CIS (GREATER-THAN OR EQUAL TO2 brain MRI lesions and GREATER-THAN OR EQUAL TO2 oligoclonal bands) enrolled in the Observational Study of Early Interferon ?-1a Treatment in High Risk Subjects after CIS study (SET study), which prospectively evaluated the effect of intramuscular interferon ?-1a treatment following the first demyelinating event. Thyroid stimulating hormone, free thyroxine,25-hydroxy vitamin D3, active smoking status and body mass index were also obtained. Clinical and MRI assessments were obtained within 4 months of the initial demyelinating event and at 6, 12 and 24 months. Results: The time to first rel
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/NT13237" target="_blank" >NT13237: Clinical and paraclinical markers of multiple sclerosis – description and prediction of disease activity</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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