Pathophysiology of Mood Disorders and Mechanisms of Action of Antidepressants and Mood Stabilizers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10193047" target="_blank" >RIV/00216208:11110/13:10193047 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-1-4614-7940-6_6" target="_blank" >http://dx.doi.org/10.1007/978-1-4614-7940-6_6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-4614-7940-6_6" target="_blank" >10.1007/978-1-4614-7940-6_6</a>
Alternative languages
Result language
angličtina
Original language name
Pathophysiology of Mood Disorders and Mechanisms of Action of Antidepressants and Mood Stabilizers
Original language description
The chapter summarizes information on the pathophysiology of mood disorders and biochemical mechanisms of action of antidepressants and mood stabilizers with focus on an endocannabinoid regulation of monoamines in depression and bipolar disorder. Leadingrole in neurochemistry and pathophysiology of mood disorders could be awarded to disturbed monoamine neurotransmission, dysfunction in energy metabolism of neurons, modulation of inflammatory and neuroendocrine pathways, and changes in activities of transcription factors, neurotrophic factors and other components involved in neuroplasticity. A role of endocannabinoid system in pathophysiology of mood disorders is supposed, but little known. In the light of new findings, there is potential for pharmacological regulation of endocannabinoid system in treatment of depressive and bipolar disorder.
Czech name
—
Czech description
—
Classification
Type
C - Chapter in a specialist book
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders
ISBN
978-1-4614-7939-0
Number of pages of the result
32
Pages from-to
103-134
Number of pages of the book
337
Publisher name
Springer
Place of publication
New York
UT code for WoS chapter
—