Nodal status is not a prognostic factor in patients with HPV-positive oral/oropharyngeal tumors
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10195283" target="_blank" >RIV/00216208:11110/13:10195283 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/13:10195283 RIV/00023736:_____/13:00010471
Result on the web
<a href="http://dx.doi.org/10.1002/jso.23292" target="_blank" >http://dx.doi.org/10.1002/jso.23292</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jso.23292" target="_blank" >10.1002/jso.23292</a>
Alternative languages
Result language
angličtina
Original language name
Nodal status is not a prognostic factor in patients with HPV-positive oral/oropharyngeal tumors
Original language description
Objectives The primary aim is to compare the prognostic parameters in patients with HPV-positive and HPV-negative tumors. The secondary aim is to compare the patterns of treatment failure between these groups. Methods Analysis of prognostic factors in agroup of 170 patients. Results High-risk HPV DNA was detected in 98 cases, 72 tumors were HPV negative. Both the overall and disease-specific survival rates were better in HPV-positive patients. In patients with HPV-negative tumors, the prognostic factors in univariate analysis were pT and pN classification, tumor stage, number of positive nodes, and extracapsular spread. Stage, pT, higher pN, and number of nodes maintained statistical significance after adjustment. None of the studied prognostic factors was significant in the group of patients with HPV-positive tumors. There was a significant difference in the localregional recurrence rates37% in HPV-negative cases and 18% in HPV-positive cases. Conclusion The characteristics of the ex
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT12483" target="_blank" >NT12483: Relation of viral etiology of oropharyngeal tumors to the response rate of individual treatment modalities</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Surgical Oncology
ISSN
0022-4790
e-ISSN
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Volume of the periodical
107
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
625-633
UT code for WoS article
000317939400013
EID of the result in the Scopus database
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