Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10195292" target="_blank" >RIV/00216208:11110/13:10195292 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/13:10195292
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pmed.1001551" target="_blank" >http://dx.doi.org/10.1371/journal.pmed.1001551</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pmed.1001551" target="_blank" >10.1371/journal.pmed.1001551</a>

Result language
angličtina
Original language name
Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development
Original language description
Background: Endometrial cancer incidence is continuing to rise in the wake of the current ageing and obesity epidemics. Much of the risk for endometrial cancer development is influenced by the environment and lifestyle. Accumulating evidence suggests that the epigenome serves as the interface between the genome and the environment and that hypermethylation of stem cell polycomb group target genes is an epigenetic hallmark of cancer. The objective of this study was to determine the functional role of epigenetic factors in endometrial cancer development.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
—

Project
<a href="/en/project/7E13033" target="_blank" >7E13033: Epigenetics for female personalized cancer care</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)