ABO blood groups and pancreatic cancer risk and survival: Results from the PANcreatic Disease ReseArch (PANDoRA) consortium
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10210040" target="_blank" >RIV/00216208:11110/13:10210040 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/13:00396181 RIV/75010330:_____/13:00010092
Result on the web
<a href="http://dx.doi.org/10.3892/or.2013.2285" target="_blank" >http://dx.doi.org/10.3892/or.2013.2285</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3892/or.2013.2285" target="_blank" >10.3892/or.2013.2285</a>
Alternative languages
Result language
angličtina
Original language name
ABO blood groups and pancreatic cancer risk and survival: Results from the PANcreatic Disease ReseArch (PANDoRA) consortium
Original language description
There is strong epidemiologic evidence indicating that common genetic variability could be implicated in pancreatic cancer risk and, to date, various loci have been proposed. In particular, there is increasing evidence of the involvement of ABO gene variability and pancreatic cancer risk. In a large multicentric study of 1,028 pancreatic ductal adenocarcinoma cases and 2,257 controls in the context of the PANcreatic Disease ReseArch (PANDoRA) consortium, we investigated the suggested association with increased risk for carriers of single nucleotide polymorphisms (SNPs) determining the A or B allele in comparison with the 0 allele, which encodes for a non-functional enzyme. Since glycosyltransferase activity, encoded by ABO, is higher for the A1 variantcompared with the A2 variant, we investigated the hypothesis that A1 carriers were at an increased risk of pancreatic cancer. In our analysis, carriers of the A1 were indeed at greater risk of developing the disease. In addition, we inve
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Oncology Reports
ISSN
1021-335X
e-ISSN
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Volume of the periodical
29
Issue of the periodical within the volume
4
Country of publishing house
GR - GREECE
Number of pages
8
Pages from-to
1637-1644
UT code for WoS article
000316510600050
EID of the result in the Scopus database
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