Treatment of high risk prostate cancer with combined radiotherapy and hormonal treatment- results and identification of factors influencing outcome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10210254" target="_blank" >RIV/00216208:11110/13:10210254 - isvavai.cz</a>

Alternative codes found

RIV/00843989:_____/13:E0103451

Result on the web

<a href="http://www.jbuon.com/pdfs/18.pdf" target="_blank" >http://www.jbuon.com/pdfs/18.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Treatment of high risk prostate cancer with combined radiotherapy and hormonal treatment- results and identification of factors influencing outcome

Original language description

Purpose: The aim of this work was to prospectively analyze the outcome of combined hormonal treatment and radical radiotherapy in high risk non metastatic prostate cancer patients (T1-4, N0-1, M0). Methods: Between April 2003 and December 2007 196 patients with high risk prostate cancer were treated with curative intent. The treatment consisted of 2-month neoadjuvant hormonal treatment (LHRH analog), radical radiotherapy (68-78 Gy, conformal technique) and an optional 2-year adjuvant hormonal treatment.Results: The median follow up time was 59 months. Five-year overall survival was 86% and 5-year biochemical disease free survival (DFS) 70%. Factors found to be statistically significant relative to outcomes were Gleason score (p=0.017), initial PSA value (p=0.039) and adjuvant hormonal treatment (p=0.035). There was no significant association between radiotherapy dose or volume and biochemical DFS (bDFS). Late genitourinary and gastrointestinal toxicity was acceptable. Conclusion: Trea

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of B.U.ON.

ISSN

1107-0625

e-ISSN

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Volume of the periodical

18

Issue of the periodical within the volume

3

Country of publishing house

GR - GREECE

Number of pages

6

Pages from-to

669-674

UT code for WoS article

000325232400018

EID of the result in the Scopus database

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