Detection of Helicobacter pylori in oropharyngeal lymphatic tissue with real-time PCR and assessment of its carcinogenic potential
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10195521" target="_blank" >RIV/00216208:11110/14:10195521 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/14:10195521 RIV/00023761:_____/14:#0000464 RIV/00064203:_____/14:10195521 RIV/00064165:_____/14:10195521
Result on the web
<a href="http://dx.doi.org/10.1007/s00405-013-2574-1" target="_blank" >http://dx.doi.org/10.1007/s00405-013-2574-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00405-013-2574-1" target="_blank" >10.1007/s00405-013-2574-1</a>
Alternative languages
Result language
angličtina
Original language name
Detection of Helicobacter pylori in oropharyngeal lymphatic tissue with real-time PCR and assessment of its carcinogenic potential
Original language description
Helicobacter pylori (HP) is considered a major gastric pathogen with oncogenic potential. The aim of this study was to determine whether HP is present in oropharyngeal lymphoid tissue and whether oropharyngeal HP strains carry virulence factor genes known to be involved in gastric carcinogenesis. The study included 104 subjects (41 patients with tonsillar carcinoma, 38 with chronic tonsillitis and 25 with obstructive sleep apnoea syndrome-OSAS). Detection of specific serum anti-HP antibodies was performed with an ELISA. The presence of HP in tissue was determined by culture and real-time PCR. Detection of virulence factors genes was also performed. Specific antibodies were found in 78.05 % of tumour cases, 34.21 % of chronic tonsillitis cases, and 72.0% of OSAS cases. The presence of HP in the tissue was detected in 73.91 % of tonsillar tumours, 70.0 % of tonsillitis cases, and 69.23 % of OSAS specimens. The results of the virulence factor gene analysis showed the majority of the s1b
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11523" target="_blank" >NT11523: Correlation of Helicobacter pylori and gastroesophageal rephlux to etiopathogenesis of oropharyngeal and laryngeal tumors</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Archives of Oto-Rhino-Laryngology
ISSN
0937-4477
e-ISSN
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Volume of the periodical
271
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
399-405
UT code for WoS article
000329996400028
EID of the result in the Scopus database
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