Pregnancy-associated plasma protein A associates with cardiovascular events in diabetic hemodialysis patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10281830" target="_blank" >RIV/00216208:11110/14:10281830 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10281830

Result on the web

<a href="http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.003" target="_blank" >http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.003" target="_blank" >10.1016/j.atherosclerosis.2014.07.003</a>

Result language

angličtina

Original language name

Pregnancy-associated plasma protein A associates with cardiovascular events in diabetic hemodialysis patients

Original language description

Objective: Pregnancy-associated plasma protein A (PAPP-A) has prognostic impact in pregnancy and acute coronary syndrome. Patients with chronic kidney disease have an excessive cardiovascular risk. In an effort to identify novel risk factors for cardiovascular disease, we investigated the relationship of PAPP-A with specific outcomes in diabetic patients undergoing dialysis. Methods: PAPP-A was measured in 1098 diabetic hemodialysis patients, who participated in the German Diabetes and Dialysis Study and followed-up for a median of 4 years. By Cox regression analysis, we assessed the association of baseline levels of PAPP-A with all-cause mortality, combined cardiovascular events and the specific outcomes of sudden death, stroke, myocardial infarctionand infectious mortality. Results: Patients had a mean age of 66 +/- 8 years (54% male) and median PAPP-A concentration of 17 mIU/L (IQR 13.4-20.9 mIU/L). Per standard deviation increase in PAPP-A the adjusted risk of sudden cardiac death

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Atherosclerosis

ISSN

0021-9150

e-ISSN

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Volume of the periodical

236

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

263-269

UT code for WoS article

000342414700026

EID of the result in the Scopus database

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