Validation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10282565" target="_blank" >RIV/00216208:11110/14:10282565 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/14:00059162 RIV/00064165:_____/14:10282565
Result on the web
<a href="http://dx.doi.org/10.1038/ki.2014.63" target="_blank" >http://dx.doi.org/10.1038/ki.2014.63</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/ki.2014.63" target="_blank" >10.1038/ki.2014.63</a>
Alternative languages
Result language
angličtina
Original language name
Validation of the Oxford classification of IgA nephropathy in cohorts with different presentations and treatments
Original language description
The Oxford Classification of IgA Nephropathy (IgAN) identified mesangial hypercellularity (M), endocapillary proliferation (E), segmental glomerulosclerosis (S), and tubular atrophy/interstitial fibrosis (T) as independent predictors of outcome. Whetherit applies to individuals excluded from the original study and how therapy influences the predictive value of pathology remain uncertain. The VALIGA study examined 1147 patients from 13 European countries that encompassed the whole spectrum of IgAN. Overa median follow-up of 4.7 years, 86% received renin-angiotensin system blockade and 42% glucocorticoid/immunosuppressive drugs. M, S. and T lesions independently predicted the loss of estimated glomerular filtration rate (eGFR) and a lower renal survival. Their value was also assessed in patients not represented in the Oxford cohort. In individuals with eGFR less than 30 ml/min per 1.73 m(2), the M and T lesions independently predicted a poor survival. In those with proteinuria under 0.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Kidney International
ISSN
0085-2538
e-ISSN
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Volume of the periodical
86
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
828-836
UT code for WoS article
000342881000022
EID of the result in the Scopus database
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