Corticosteroids in IgA Nephropathy: A Retrospective Analysis from the VALIGA Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10297823" target="_blank" >RIV/00216208:11110/15:10297823 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/15:00059666 RIV/00064165:_____/15:10297823
Result on the web
<a href="http://dx.doi.org/10.1681/ASN.2014070697" target="_blank" >http://dx.doi.org/10.1681/ASN.2014070697</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1681/ASN.2014070697" target="_blank" >10.1681/ASN.2014070697</a>
Alternative languages
Result language
angličtina
Original language name
Corticosteroids in IgA Nephropathy: A Retrospective Analysis from the VALIGA Study
Original language description
Current guidelines suggest treatment with corticosteroids (CS) in IgA nephropathy (IgAN) when proteinuria is persistently >1 g/d despite 3-6 months of supportive care and when eGFR is >50 ml/min per 1.73 m2. Whether the benefits of this treatment extendto patients with an eGFR50 ml/min per 1.73 m2, other levels of proteinuria, or different renal pathologic lesions remains unknown. We retrospectively studied 1147 patients with IgAN from the European Validation Study of the Oxford Classification of IgAN(VALIGA) cohort classified according to the Oxford-MEST classification and medication used, with details of duration but not dosing. Overall, 46% of patients received immunosuppression, of which 98% received CS. Treated individuals presented with greaterclinical and pathologic risk factors of progression. They also received more antihypertensive medication, and a greater proportion received renin angiotensin system blockade (RASB) compared with individuals without immunosuppressive ther
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of the American Society of Nephrology : JASN
ISSN
1046-6673
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
9
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
2248-2258
UT code for WoS article
000360582100021
EID of the result in the Scopus database
2-s2.0-84940779394