Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284014" target="_blank" >RIV/00216208:11110/14:10284014 - isvavai.cz</a>
Result on the web
<a href="http://www.dovepress.com/sensory-disturbances-inhibitory-deficits-and-the-p50-wave-in-schizophr-peer-reviewed-article-NDT" target="_blank" >http://www.dovepress.com/sensory-disturbances-inhibitory-deficits-and-the-p50-wave-in-schizophr-peer-reviewed-article-NDT</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/NDT.S64219" target="_blank" >10.2147/NDT.S64219</a>

Result language
angličtina
Original language name
Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia
Original language description
Sensory gating disturbances in schizophrenia are often described as an inability to filter redundant sensory stimuli that typically manifest as inability to gate neuronal responses related to the P50 wave, characterizing a decreased ability of the brainto inhibit various responses to insignificant stimuli. It implicates various deficits of perceptual and attentional functions, and this inability to inhibit, or "gate", irrelevant sensory inputs leads to sensory and information overload that also may result in neuronal hyperexcitability related to disturbances of habituation mechanisms. These findings seem to be particularly important in the context of modern electrophysiological and neuroimaging data suggesting that the filtering deficits in schizophrenia are likely related to deficits in the integrity of connections between various brain areas. As a consequence, this brain disintegration produces disconnection of information, disrupted binding, and disintegration of consciousness that
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
—

Project
<a href="/en/project/LH11032" target="_blank" >LH11032: Dysfunctional connectivity and dissociative states.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)