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Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00079334" target="_blank" >RIV/00216224:14740/14:00079334 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.dovepress.com/sensory-disturbances-inhibitory-deficits-and-the-p50-wave-in-schizophr-peer-reviewed-article-NDT" target="_blank" >http://www.dovepress.com/sensory-disturbances-inhibitory-deficits-and-the-p50-wave-in-schizophr-peer-reviewed-article-NDT</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2147/NDT.S64219" target="_blank" >10.2147/NDT.S64219</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia

  • Original language description

    Sensory gating disturbances in schizophrenia are often described as an inability to filter redundant sensory stimuli that typically manifest as inability to gate neuronal responses related to the P50 wave, characterizing a decreased ability of the brainto inhibit various responses to insignificant stimuli. It implicates various deficits of perceptual and attentional functions, and this inability to inhibit, or "gate", irrelevant sensory inputs leads to sensory and information overload that also may result in neuronal hyperexcitability related to disturbances of habituation mechanisms. These findings seem to be particularly important in the context of modern electrophysiological and neuroimaging data suggesting that the filtering deficits in schizophrenia are likely related to deficits in the integrity of connections between various brain areas.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    NEUROPSYCHIATRIC DISEASE AND TREATMENT

  • ISSN

    1178-2021

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    July

  • Country of publishing house

    NZ - NEW ZEALAND

  • Number of pages

    7

  • Pages from-to

    1309-1315

  • UT code for WoS article

    000339065100001

  • EID of the result in the Scopus database