Thyroid Nodules: Pathophysiological Insight on Oncogenesis and Novel Diagnostic Techniques

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285457" target="_blank" >RIV/00216208:11110/14:10285457 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/14:10285457

Result on the web

<a href="http://www.biomed.cas.cz/physiolres/pdf/63/63_S263.pdf" target="_blank" >http://www.biomed.cas.cz/physiolres/pdf/63/63_S263.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Thyroid Nodules: Pathophysiological Insight on Oncogenesis and Novel Diagnostic Techniques

Original language description

Thyroid nodules are a very frequent pathology among common population. Despite the vast majority of them are of benign origin, the incidence of thyroid cancer is currently rather rising. Although there are several risk factors of thyroid cancer and several clinical, ultrasound, biochemical and molecular diagnostic markers, the exact mechanisms of thyroid oncogenesis and the linkage between thyroid nodule ultrasound appearance and its biological character remain unclear. While ionizing radiation is the only one well-known risk factor for thyroid cancer, the significance of some others remains unclear. The aim of our review was to discuss some not completely known pathophysiological mechanisms involved in thyroid oncogenesis as hypothyroidism, mutationsof genes regulating cell proliferation, thyroid autoimmunity and pregnancy and to describe pathophysiological background of some ultrasound markers of thyroid cancer (size, echogenicity, vascularization, calcifications and stiffness). Bet

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

63

Issue of the periodical within the volume

Suppl. 2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

13

Pages from-to

"S263"-"S275"

UT code for WoS article

000345590400003

EID of the result in the Scopus database

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