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Effects of teriparatide on cortical histomorphometric variables in postmenopausal women with or without prior alendronate treatment

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285482" target="_blank" >RIV/00216208:11110/14:10285482 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064165:_____/14:10285482

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bone.2013.11.011" target="_blank" >http://dx.doi.org/10.1016/j.bone.2013.11.011</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bone.2013.11.011" target="_blank" >10.1016/j.bone.2013.11.011</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effects of teriparatide on cortical histomorphometric variables in postmenopausal women with or without prior alendronate treatment

  • Original language description

    Cortical bone, the dominant component of the human skeleton by volume, plays a key role in protecting bones from fracture. We analyzed the cortical bone effects of teriparatide treatment in postmenopausal women with osteoporosis who had previously received long-term alendronate (ALN) therapy or were treatment naive (TN). Tetracycline-labeled paired iliac crest biopsies obtained from 29 ALN-pretreated and 16 TN women were evaluated for dynamic histomorphometric parameters of bone formation at the periosteal, endocortical and intracortical bone compartments, before and after 24 months of teriparatide treatment. At baseline, the frequency of specimens without any endocortical and periosteal tetracycline labeling, and the percentage of quiescent osteons, was higher in the ALN than the TN group. Endocortical and periosteal mineralizing surface (MS/BS%), periosteal bone formation rate (BFR/BS), mineral apposition rate (MAR) and the number of intracortical forming osteons were significantly l

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Bone

  • ISSN

    8756-3282

  • e-ISSN

  • Volume of the periodical

    59

  • Issue of the periodical within the volume

    February

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    139-147

  • UT code for WoS article

    000329558600018

  • EID of the result in the Scopus database