Importance of thorough investigation of resistant hypertension before renal denervation: should compliance to treatment be evaluated systematically?

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285643" target="_blank" >RIV/00216208:11110/14:10285643 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/14:43908151 RIV/00064165:_____/14:10285643
Result on the web
<a href="http://dx.doi.org/10.1038/jhh.2014.3" target="_blank" >http://dx.doi.org/10.1038/jhh.2014.3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/jhh.2014.3" target="_blank" >10.1038/jhh.2014.3</a>

Result language
angličtina
Original language name
Importance of thorough investigation of resistant hypertension before renal denervation: should compliance to treatment be evaluated systematically?
Original language description
Catheter-based renal denervation (RD) has been introduced recently as a potentially effective invasive treatment of refractory hypertension. The proportion of patients with severe hypertension suitable for RD is not clear. The aim of this study was to identify what percentage of patients has truly resistant essential hypertension and are thus potentially eligible for RD. We investigated 205 consecutive patients referred to a university hypertension center for severe hypertension within 12 months. Ambulatory 24-h blood pressure (BP) monitoring (24 h ABPM), secondary hypertension screening and compliance to treatment testing (by use of plasma drug level measurements) were performed in all patients. Fifty-seven patients (27.8%) did not have truly resistant hypertension (RH) based on clinical BP. Among the remaining 122 patients (59.5%) with RH confirmed by 24 h ABPM, 50 patients (24.4% of the original cohort) had a secondary cause of hypertension and in 27 (13.2%) non-compliance to treatm
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
<a href="/en/project/NT14155" target="_blank" >NT14155: Effect of the specific treatment of primary aldosteronism on subclinical organ damage regression</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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