Acute methanol poisonings: Folates administration and visual sequelae

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10287116" target="_blank" >RIV/00216208:11110/14:10287116 - isvavai.cz</a>

Alternative codes found

RIV/61388955:_____/14:00434535 RIV/00064165:_____/14:10287116

Result on the web

<a href="http://dx.doi.org/10.1016/j.jab.2014.04.001" target="_blank" >http://dx.doi.org/10.1016/j.jab.2014.04.001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jab.2014.04.001" target="_blank" >10.1016/j.jab.2014.04.001</a>

Result language

angličtina

Original language name

Acute methanol poisonings: Folates administration and visual sequelae

Original language description

During the outbreak of methanol poisonings in the Czech Republic 2012, we studied the clinical effectiveness of folate therapy in preventing visual damage. Data were obtained from a combined prospective and retrospective study on 79 patients: folinic acid was administered in 28, folic acid in 35; 16 patients received no folates. The groups were comparable by age, time to treatment, laboratory findings, symptoms, and treatment. The number of patients with visual sequelae differed neither between the groups treated with folinic/folic acid, nor between the groups with/without folate administration. The patients with visual sequelae were more acidotic and differed in pH, HCO3-, base deficit, anion gap, but not in methanol, ethanol, osmolal gap, formate, and pCO(2). Serum lactate, but not formate differed significantly. The higher serum glucose on admission was in the patients with visual sequelae. Regardless the rationale for folate administration in acute methanol poisoning, its clinical

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

309-316

UT code for WoS article

000345065200016

EID of the result in the Scopus database

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