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How smoking cessation influence hormonal levels in postmenopausal women?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10288246" target="_blank" >RIV/00216208:11110/14:10288246 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023761:_____/14:#0000500 RIV/00064165:_____/14:10288246

  • Result on the web

    <a href="http://pmr.cuni.cz/file/5681/PMR2014A0006.pdf" target="_blank" >http://pmr.cuni.cz/file/5681/PMR2014A0006.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    How smoking cessation influence hormonal levels in postmenopausal women?

  • Original language description

    Smoking represents the most widespread substance dependence in the world. Nicotine alters women hormonal homeostasis. Women smokers have higher testosterone and lower estradiol levels throughout life compared to nonsmokers. We monitored the effect of smoking discontinuation on steroid spectrum with 25 postmenopausal women smokers. They had been examined before discontinuation of smoking and after 6, 12, 24 and 48 weeks of abstinence. Blood was collected to determine steroid spectrum (measured by GC-MS),luteinizing hormone, follicle stimulating hormone and sex hormone binding globulin (measured by IRMA). Repeated measures ANOVA model was used for evaluation of the data. In postmenopausal women, an increase in testosterone, dihydrotestosterone, dehydroepiandrosterone and other androgens occurred. Neither nicotine replacement therapy nor weight changes nor age play a role in androgen level increase. The higher androgens levels correlated with failure in smoking cessation. Women smokers h

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FN - Epidemiology, infection diseases and clinical immunology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT12340" target="_blank" >NT12340: Extraovarian steroid hormones in the course of the menstrual cycle</a><br>

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Prague medical report

  • ISSN

    1214-6994

  • e-ISSN

  • Volume of the periodical

    115

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    60-66

  • UT code for WoS article

  • EID of the result in the Scopus database