Inflammatory myopathy associated with statins: report of three cases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10289106" target="_blank" >RIV/00216208:11110/14:10289106 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/14:10289106 RIV/00064203:_____/14:10289106 RIV/00023728:_____/14:#0004042 RIV/00064190:_____/14:#0000960 RIV/00064165:_____/14:10289106
Result on the web
<a href="http://dx.doi.org/10.3109/14397595.2013.852848" target="_blank" >http://dx.doi.org/10.3109/14397595.2013.852848</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/14397595.2013.852848" target="_blank" >10.3109/14397595.2013.852848</a>

Result language
angličtina
Original language name
Inflammatory myopathy associated with statins: report of three cases
Original language description
Statins are well-established lipid-lowering drugs that reduce morbidity and mortality due to cardiovascular disease and cause adverse effects relatively rarely. It is still unclear whether statins are capable of inducing an immune-mediated response directed against skeletal muscle. Here, we present the cases of three patients who developed inflammatory myopathy in the course of statin treatment. Moreover, multiple mitochondrial DNA deletions were found in two of them. The ability of statins to induce animmune-mediated response and their interactions with mitochondrial metabolism pathways are discussed.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
—

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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