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Laser irradiation induces mitochondrial dysfunction in hepatic cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F19%3A00521405" target="_blank" >RIV/68378041:_____/19:00521405 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378271:_____/19:00521405 RIV/00023001:_____/19:00079632

  • Result on the web

    <a href="http://dx.doi.org/10.1117/12.2527110" target="_blank" >http://dx.doi.org/10.1117/12.2527110</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1117/12.2527110" target="_blank" >10.1117/12.2527110</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Laser irradiation induces mitochondrial dysfunction in hepatic cells

  • Original language description

    Laser irradiation has been recognized as a promising tool across a number of biomedical applications. However, understanding the molecular mechanisms and cellular responses remains incomplete. Here, we investigated the mechanism involved in the apoptotic process in human hepatic cells under laser irradiation. Our data show that the laser-mediated alternation of mitochondrial membrane potential leads apoptosis in Huh7 and Alexander cells. Contrary, HepG2 cells are resistant to laser induced cell death. The observed link between mitochondrial membrane potential and cytotoxicity could be a fundamental phenomenon in laser-induced cell apoptosis.n

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10610 - Biophysics

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Medical Laser Applications and Laser-Tissue Interactions IX

  • ISBN

    978-151062851-9

  • ISSN

    0277-786X

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    1-4

  • Publisher name

    SPIE

  • Place of publication

    Bellingham

  • Event location

    Munich

  • Event date

    Jun 23, 2019

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article